Life & Death of Spiders. Which came first, the radiation or the powers? Was the radioactive spider-bite that granted Peter Parker his amazing abilities an accident. . .or something more? Now, the mysterious Ezekiel offers him a shocking explanation: Peter may be the latest in an ancient line of humans gifted with supernatural spider-powers. But Peter won't have much time to ponder his origins, as his existence has drawn the attention of Shathra, an otherworldly being who sees Spider-Man as her prey. Overpowered and on the run, the web-slinger has only his wits and courage to keep him from becoming Shathra's next meal. The Life & Death of Spiders also features the long-awaited reunion of Mary Jane and Peter. With one last chance to be together, will this couple finally reconcile? This book collects: Amazing Spider-Man Vol. 2 #s 46-50